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Pregnancy in infertile PCOD patients. Complications and outcome
1Department of Obstetrics and Gynecology, University of Hacettepe, Faculty of Medicine, Ankara, Turkey.
Objective:
To evaluate the complications and outcome of pregnancy in women with polycystic ovary disease (PCOD).
Study Design:
The course and outcome of 47 singleton pregnancies in women with well-documented PCOD were compared with those in 100 healthy controls.
Results:
Women with PCOD had a significantly higher body mass index as compared to the control group (P < .05); however, the proportion of lean versus obese subjects in the two groups was similar. The incidence of an abnormal glucose challenge test, gestational diabetes mellitus and pregnancy-induced hypertension was significantly increased in pregnant women with PCOD (P < .05). When lean PCOD subjects were compared with lean control subjects, the difference in the incidence of the above complications was still significant (P < .05). The incidence of pregnancy complications was similar when obese PCOD subjects were compared with obese controls.
Conclusion:
Women with PCOD were at increased risk of gestational diabetes and pregnancy-induced hypertension, and this risk appeared to be independent of body mass index.