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Effect of maternally administered heroin on the motor activity of rat offspring
The behavioral of 21-day old rats whose mothers were administered heroin (5 mg/kg daily) throughout gestation and lactation was studied utilizing an activity wheel, activity cage, open field test, and step-down latency times from an elevated platform. The total score of all behavioral tasks of offspring from heroin-injected females was statistically different from that of pups from saline-injected mothers, with heroin-treated animals appearing more active.
The behavioral of 21-day old rats whose mothers were administered heroin (5 mg/kg daily) throughout gestation and lactation was studied utilizing an activity wheel, activity cage, open field test, and step-down latency times from an elevated platform. The total score of all behavioral tasks of offspring from heroin-injected females was statistically different from that of pups from saline-injected mothers, with heroin-treated animals appearing more active.