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DNA repair: caretakers of the genome?
1Department of Biological Sciences, SUNY at Albany, 1400 Washington Avenue, Albany, New York 12222, USA.
Current Biology : CB
|September 1, 1997
Abstract:
Recent results show that the 8-oxoguanine DNA repair system is functionally conserved in bacteria and mammals. The bacterial system protects the genome from the mutagenic effects of oxidative stress; the role of the mammalian system is expected to be similar and defects in it may increase susceptibility to cancer.