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Tumor-induced osteomalacia: clinical and basic studies

E Shane1, M Parisien, J E Henderson

  • 1Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, New York, USA.

Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research
|September 1, 1997
PubMed
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This study details a patient with tumor-induced osteomalacia successfully treated by chondroma resection. The findings suggest a tumor product affecting 1,25-dihydroxyvitamin D and phosphorus metabolism, and potentially stimulating bone resorption.

Area of Science:

  • Endocrinology
  • Oncology
  • Bone Metabolism

Background:

  • Tumor-induced osteomalacia is a rare disorder characterized by hypophosphatemia and phosphaturia.
  • It is often caused by benign tumors that secrete phosphaturic substances.
  • Diagnosis and management can be challenging due to the rarity and varied presentation.

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