Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Fever: friend or enemy?]

M P Fischler1, W H Reinhart

  • 1Medizinische Klinik, Rätisches Kantons-und Regionalspital, Chur.

Schweizerische Medizinische Wochenschrift
|May 17, 1997
PubMed
Summary
This summary is machine-generated.

Normal body temperature varies, with higher acceptable limits in the morning and afternoon. Fever and hyperthermia are distinct, requiring different treatments, and fever management should not be routine.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Influence of parenteral nutrition on blood rheology and platelet aggregation in vitro.

Biorheology·2014
Same author

Fatigue in multiple sclerosis is not due to sleep apnoea.

European journal of neurology·2013
Same author

Cocaine in high concentrations inhibits platelet aggregation in vitro.

Clinical hemorheology and microcirculation·2013
Same author

The passage of a hemodialysis filter affects hemorheology, red cell shape, and platelet aggregation.

Clinical hemorheology and microcirculation·2013
Same author

[Histoplasmosis - an unusual African souvenir].

Deutsche medizinische Wochenschrift (1946)·2013
Same author

Studies on metabolically depleted erythrocytes.

Clinical hemorheology and microcirculation·2013

Area of Science:

  • Physiology
  • Thermoregulation

Context:

  • Normal body temperature exhibits circadian variation, challenging the fixed upper limit of 37°C.
  • Fever results from a raised hypothalamic thermostatic set point, while hyperthermia involves a failure of thermoregulation.
  • Increased body temperature has both beneficial and detrimental effects.

Purpose:

  • To redefine normal body temperature ranges considering circadian rhythms.
  • To differentiate between fever and hyperthermia and their underlying mechanisms.
  • To inform clinical practice regarding the management of elevated body temperature.

Summary:

  • Normal body temperature is Gaussian and circadian, suggesting updated upper limits (37.1°C morning, 37.4°C afternoon).
  • Fever involves cytokine-induced thermostatic set point elevation, leading to increased heat production and decreased dissipation.

Related Experiment Videos

  • Hyperthermia occurs when the thermostatic set point is normal, but heat control mechanisms fail.

    • Impact:

    • Revising normal temperature thresholds may refine fever diagnosis.
    • Distinguishing fever from hyperthermia is crucial for appropriate treatment selection.
    • Judicious use of antipyretics and targeted cooling strategies are recommended based on the underlying cause of elevated temperature.