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Updated: Aug 8, 2026

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Corneal Epithelial Abrasion with Ocular Burr As a Model for Cornea Wound Healing
Published on: July 10, 2018
Corneal infiltration after recurrent corneal epithelial erosion
A C Ionides1, S J Tuft, V M Ferguson
1Moorfields Eye Hospital, London.
The British Journal of Ophthalmology
|July 1, 1997
Summary
Acute corneal infiltrates are an uncommon complication of recurrent corneal epithelial erosion. Despite intense inflammation, most cases resolve quickly with good vision and may end further erosion symptoms.
Area of Science:
- Ophthalmology
- Corneal Diseases
- Microbial Keratitis
Background:
- Recurrent corneal epithelial erosion (RCEE) is a common condition.
- Acute corneal infiltration can be a complication of RCEE.
Observation:
- A retrospective review of 11 patients with RCEE who developed acute corneal infiltration was conducted.
- Typical presentation included a paracentral epithelial defect, stromal infiltrate, and anterior uveitis.
- Bacterial culture was positive in only 16% of episodes.
Findings:
- Corneal infiltrates in RCEE patients are often culture-negative.
- Treatment with topical antibiotics and corticosteroids led to rapid healing and reduced inflammation.
- All patients achieved good visual outcomes, with minimal recurrence of RCEE symptoms.
Implications:
- Corneal infiltrates, though uncommon in RCEE, typically resolve well with prompt treatment.
- These infiltrative episodes may signal an end to recurrent epithelial erosion symptoms.
- Ophthalmologists should consider RCEE as a potential underlying factor in patients presenting with corneal infiltrates.

