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Plasma endothelin-1 and tumor necrosis factor-alpha concentrations in pregnant and cyclic rats after low-dose
M M Faas1, W W Bakker, N Valkhof
1Department of Obstetrics and Gynecology, University of Groningen, The Netherlands.
American Journal of Obstetrics and Gynecology
|August 1, 1997
Abstract:
Plasma endothelin-1 and tumor necrosis factor-alpha were determined in pregnant and cyclic rats after infusion of either endotoxin (1.0 microgram/kg of body weight) or saline solution. After endotoxin, but not after saline solution, administration there was a transient endothelin-1 response in pregnant rats but not cyclic rats. In both reproductive conditions there was an equally high transient tumor necrosis factor-alpha response after endotoxin.