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Published on: November 23, 2017
Surgical treatment of dermatofibrosarcoma protuberans
E J Arnaud1, M Perrault, M Revol
1Department of Plastic Surgery, Hôpital Saint-Louis, Paris, France.
Plastic and Reconstructive Surgery
|September 18, 1997
Summary
Wide surgical resection of dermatofibrosarcoma protuberans (DFSP) prevents recurrence. Aggressive primary treatment of this rare skin cancer offers the best prognosis, minimizing malignant transformation and metastasis.
Area of Science:
- Dermatologic Surgery
- Surgical Oncology
- Oncology
Background:
- Dermatofibrosarcoma protuberans (DFSP) is a rare, locally aggressive skin tumor.
- Inadequate primary treatment often leads to tumor recurrence.
- Recurrent DFSP carries a risk of malignant transformation and metastasis.
Purpose of the Study:
- To evaluate the outcomes of surgical treatment for DFSP.
- To compare the efficacy of wide versus narrow resection margins.
- To assess the impact of primary treatment on recurrence and prognosis.
Main Methods:
- Retrospective analysis of 117 patients with DFSP.
- Surgical treatment involving wide peripheral (5 cm) and deep resection.
- Mean follow-up of 61 months.
Main Results:
- No recurrence in 66 patients treated with primary wide resection.
- 2 of 41 patients with recurrent DFSP developed further local disease.
- Both patients with secondary recurrence eventually died of metastatic fibrosarcoma.
Conclusions:
- Highly aggressive primary resection is crucial for DFSP management.
- Minimizing local recurrence prevents malignant transformation and metastasis.
- Radical primary resection with immediate reconstruction offers the best patient outcomes.
