Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Factor X deficiency in a cat

J L Gookin1, M B Brooks, J L Catalfamo

  • 1Department of Companion Animal and Special Species Medicine, College of Veterinary Medicine, North Carolina State University, Raleigh 27606, USA.

Journal of the American Veterinary Medical Association
|September 18, 1997
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Impact of Pharmacogenetics on Pharmacokinetics of First-Line Antituberculosis Drugs in the HIRIF Trial.

The Journal of infectious diseases·2025
Same author

TB yields from expanded contact tracing investigations.

Public health action·2025
Same author

Evaluation of treatment outcomes and associated risk factors in children with TB in Bangladesh.

Public health action·2025
Same author

Application of a TB care cascade to a novel household contact intervention in rural South Africa.

Public health action·2024
Same author

Effects of alfaxalone, propofol and isoflurane on cerebral blood flow and cerebrovascular reactivity to carbon dioxide in dogs: A pilot study.

Veterinary journal (London, England : 1997)·2022
Same author

A structured community engagement strategy to support uptake of TB active case-finding.

Public health action·2022
Same journal

Acute-onset neurologic signs in an indoor/outdoor domestic shorthair cat.

Journal of the American Veterinary Medical Association·2026
Same journal

Progressive exophthalmos and strabismus in a 4-year-old Jersey steer.

Journal of the American Veterinary Medical Association·2026
Same journal

Orchiectomy in horses: closed technique and primary closure of the incision.

Journal of the American Veterinary Medical Association·2026
Same journal

Stranguria in a 3-month-old Holstein-Friesian heifer.

Journal of the American Veterinary Medical Association·2026
Same journal

Caudal vena cava-to-aorta ratio in hemodynamically stable and unstable client-owned rabbits.

Journal of the American Veterinary Medical Association·2026
Same journal

Dogs with intrahepatic portal hypertension of congenital cause have distinct diagnostic findings compared to dogs with chronic hepatitis-related portal hypertension.

Journal of the American Veterinary Medical Association·2026
See all related articles

Severe congenital factor X deficiency, a rare bleeding disorder, was diagnosed in a domestic shorthair cat. This finding highlights the need for specific coagulation factor analysis in diagnosing feline coagulopathies.

Area of Science:

  • Veterinary Medicine
  • Hematology
  • Genetics

Background:

  • Congenital factor X deficiency is a rare inherited bleeding disorder affecting multiple species.
  • Coagulopathies in cats can present with diverse clinical signs, complicating diagnosis.

Observation:

  • A 3-year-old domestic shorthair cat presented with generalized seizures and prolonged bleeding post-venipuncture.
  • Screening tests revealed a prolonged Russell's viper venom time in the dam and reduced factor X activity in the dam and a sibling.

Findings:

  • The study reports the first known case of severe congenital factor X deficiency in a domestic cat.
  • Evidence suggests a hereditary basis for factor X deficiency in this feline family.

Implications:

Related Experiment Videos

  • This case expands the known spectrum of inherited coagulopathies in domestic animals.
  • Accurate diagnosis of feline bleeding disorders may necessitate advanced coagulation factor analysis beyond standard screening tests.