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Polymorphonuclear leukocytes: possible mechanism of accumulation in psoriasis
Science (New York, N.Y.)
|December 16, 1977
Abstract:
Extracts of involved and uninvolved skin from nine patients with untreated psoriasis were studied for chemotactic activity. Psoriatic plaque contains increased amounts of a complement-dependent chemotactic factor that is inhibited by diisopropyl fluorophosphate. This factor may be human skin serine proteinase.