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Synthesis and antimicrobial activity of N, N-dialkyl-2-substituted-5-diazo-imidazole-4-carboxamides
L Varoli1, S Burnelli, L Garuti
1Dipartimento di Scienze Farmaceutiche, Università di Bologna, Italy.
Die Pharmazie
|August 1, 1997
Abstract:
A series of 2-substituted-5-diazoimidazole-4-carboxamides has been synthesized, and their antimicrobial activity has been tested in vitro. Some of the compounds show antifungal activity related to the presence of small groups on the 4-carbox-amido moiety, while the presence of substituents in position 2 was detrimental.