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Synthesis and antimicrobial activities of some new 2-substituted benzoxazole/benzothiazole derivatives
H M el-Shaaer1, S A Abdel-Aziz, H A Allimony
1Department of Chemistry, Faculty of Education, Ain-Shams University, Roxy, Cairo.
Die Pharmazie
|August 1, 1997
Abstract:
In the search for new antimicrobial compounds, several new sulfur bearing heterobicyclic moieties (4-11) have been synthesized by acylation and alkylation of acetamide, thioacetamide and semicarbazide derivatives. The structure of the products was deduced from elemental analyses as well as spectral data (IR, 1H NMR and MS). Significant antimicrobial activities were obtained for all new compounds especially against Fusarium oxysporum.