Related Experiment Videos
Prolongation of prothrombin time with the use of indomethacin and warfarin
1Department of Clinical Pharmacology, Prince of Wales Hospital, Shatin, Hong Kong.
The British Journal of Clinical Practice
|April 1, 1997
Abstract:
A patient with a greatly prolonged international normalised ratio (INR) during the combined use of warfarin and indomethacin is described. In patients on warfarin, non-steroidal anti-inflammatory drugs (NSAIDs) should be avoided as far as possible. If NSAIDs are absolutely necessary, patients should be closely monitored for prolongation of INR and bleeding.