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Clearance of cervical human papillomavirus infection by treatment for cervical dysplasia
L J Bollen1, S P Tjong-A-Hung, J van der Velden
1Department of Virology, University of Amsterdam, Academic Medical Center, The Netherlands.
Objectives:
The aim of this study was to investigate the prevalence of human papillomavirus (HPV) after treatment for cervical dysplasia.
Study Design:
The presence of HPV was investigated in cervical scrapes of 91 patients, before and after treatment, using consensus primers in the polymerase chain reaction.
Results:
Before treatment for cervical dysplasia, 89 of 91 patients (98%) were HPV-positive compared with 28 of 91 patients (31%) after treatment. The HPV type present before treatment was found in the scrapes of only 9 of 89 patients (10%). Detection of HPV after treatment was associated with human immunodeficiency virus infection and incomplete conization.
Conclusion:
The HPV type present before treatment was frequently cleared by treatment for cervical dysplasia.