IRF-1: the transcription factor linking the interferon response and oncogenesis

Type I interferons are essential mediators of apoptotic death in virally infected cells.

Genes to cells : devoted to molecular & cellular mechanisms·1998

DNA damage-induced apoptosis and Ice gene induction in mitogenically activated T lymphocytes require IRF-1.

Leukemia·1997

Cooperation of the tumour suppressors IRF-1 and p53 in response to DNA damage.

Nature·1996

An IRF-1-dependent pathway of DNA damage-induced apoptosis in mitogen-activated T lymphocytes.

Nature·1995

Accelerated exon skipping of IRF-1 mRNA in human myelodysplasia/leukemia; a possible mechanism of tumor suppressor inactivation.

Oncogene·1994

Cellular commitment to oncogene-induced transformation or apoptosis is dependent on the transcription factor IRF-1.

Cell·1994

Oligomeric state of the light-harvesting complexes B800-850 and B875 from purple bacterium Rubrivivax gelatinosus in detergent solution.

Biochimica et biophysica acta·2019

Regulation of pigment content and enzyme activity in the cyanobacterium Nostoc sp. Mac grown in continuous light, a light-dark photoperiod, or darkness.

Biochimica et biophysica acta·2019

Location of the calcium binding site in Photosystem II: A Mn2+ substitution study.

Biochimica et biophysica acta·2019

The role of acidic residues of plastocyanin in its interaction with cytochrome ƒ.

Biochimica et biophysica acta·2019

Influence of KF, DCMU and removal of Ca+ on the high-spin EPR signal of the cytochrome b-559 heme Fe(III) ligated by OH- in chloroplasts.

Biochimica et biophysica acta·2019

The importance of being (slightly) modified: The role of rRNA editing on gene expression control and its connections with cancer.

Biochimica et biophysica acta·2016

Lycium barbarum glycopeptide protects against inherited retinal degeneration in rd10 mice by regulating phototransduction and neuroinflammatory pathways.

Neural regeneration research·2026

Neuronal Ddit4 overexpression in the medial prefrontal cortex reduces synaptic density and impairs cognitive function in mice.

eNeuro·2026

Exosome therapy for knee osteoarthritis: a network meta-analysis based on rat models.

Stem cells translational medicine·2026

Tobacco and Marijuana Induce Adverse Effects on Cardiac Function and Platelet Activity and Reduce Tissue Preservation Following Myocardial Infarction.

American journal of physiology. Heart and circulatory physiology·2026

Danburstotug, an anti-PD-L1 antibody, in relapsed/refractory extra-nodal natural killer/T-cell lymphoma: The phase 2 DISTINKT study.

British journal of haematology·2026

Targeting AHNAK ameliorates osteonecrosis of the femoral head and affects adipogenic pathways involving Smad/PPARγ.

Bone & joint research·2026

Related Experiment Videos

IRF-1: the transcription factor linking the interferon response and oncogenesis

Related Concept Videos

Type I interferons are essential mediators of apoptotic death in virally infected cells.

DNA damage-induced apoptosis and Ice gene induction in mitogenically activated T lymphocytes require IRF-1.

Cooperation of the tumour suppressors IRF-1 and p53 in response to DNA damage.

An IRF-1-dependent pathway of DNA damage-induced apoptosis in mitogen-activated T lymphocytes.

Accelerated exon skipping of IRF-1 mRNA in human myelodysplasia/leukemia; a possible mechanism of tumor suppressor inactivation.

Cellular commitment to oncogene-induced transformation or apoptosis is dependent on the transcription factor IRF-1.

Oligomeric state of the light-harvesting complexes B800-850 and B875 from purple bacterium Rubrivivax gelatinosus in detergent solution.

Regulation of pigment content and enzyme activity in the cyanobacterium Nostoc sp. Mac grown in continuous light, a light-dark photoperiod, or darkness.

Location of the calcium binding site in Photosystem II: A Mn2+ substitution study.

The role of acidic residues of plastocyanin in its interaction with cytochrome ƒ.

Influence of KF, DCMU and removal of Ca+ on the high-spin EPR signal of the cytochrome b-559 heme Fe(III) ligated by OH- in chloroplasts.

The importance of being (slightly) modified: The role of rRNA editing on gene expression control and its connections with cancer.

Lycium barbarum glycopeptide protects against inherited retinal degeneration in rd10 mice by regulating phototransduction and neuroinflammatory pathways.

Neuronal Ddit4 overexpression in the medial prefrontal cortex reduces synaptic density and impairs cognitive function in mice.

Exosome therapy for knee osteoarthritis: a network meta-analysis based on rat models.

Tobacco and Marijuana Induce Adverse Effects on Cardiac Function and Platelet Activity and Reduce Tissue Preservation Following Myocardial Infarction.

Danburstotug, an anti-PD-L1 antibody, in relapsed/refractory extra-nodal natural killer/T-cell lymphoma: The phase 2 DISTINKT study.

Targeting AHNAK ameliorates osteonecrosis of the femoral head and affects adipogenic pathways involving Smad/PPARγ.

Related Experiment Videos

IRF-1: the transcription factor linking the interferon response and oncogenesis

Related Concept Videos

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