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[Malignant hemangioendothelioma associated with chronic pyothorax]
1First Department of Internal Medicine, Gunma University School of Medicine, Japan.
Nihon Kyobu Shikkan Gakkai Zasshi
|June 1, 1997
Summary
Malignant hemangioendothelioma, a rare vascular tumor, was diagnosed in a patient with chronic empyema. Autopsy revealed atypical cells forming vascular structures, confirming this rare diagnosis.
Area of Science:
- Oncology
- Pathology
- Thoracic Surgery
Background:
- Malignant hemangioendothelioma is a rare vascular neoplasm.
- Chronic empyema can present with complex thoracic findings.
- Accurate diagnosis of rare thoracic tumors can be challenging.
Observation:
- A 67-year-old male presented with fever and was found to have multilobular heterogeneous shadows on chest CT.
- Initial clinical and biopsy examinations were inconclusive.
- Autopsy revealed a hemorrhagic tumor in the chest wall.
Findings:
- Microscopical examination showed atypical cells forming vascular structures.
- Immunohistochemical staining was positive for anti-factor VIII antibody.
- The histological findings confirmed a diagnosis of malignant hemangioendothelioma.
Implications:
- This case highlights the rarity of chronic empyema-associated malignant hemangioendothelioma.
- It underscores the importance of comprehensive autopsy in diagnosing challenging thoracic pathologies.
- Further research into the pathogenesis and treatment of this rare entity is warranted.