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Transurethral microwave thermotherapy in symptomatic benign prostatic hyperplasia: a possible association between
1Department of Urology, Karolinska Institute, Huddinge University Hospital, Sweden.
Background:
Nothing is yet known of possible endocrine effects of transurethral microwave thermotherapy (TUMT) or of possible influence of endocrine status on the result of thermotherapy.
Methods:
Serum levels of testosterone (T), SHBG, estradiol, LH, and PSH were measured in 48 men with BPH before and 2-3 months after TUMT (Prostatron, Prostasoft 2.0; Technomed International, Lyon, France). Assessment of results was based on the patients' own estimations.
Results:
The treatment did not alter hormone levels. Patients who reported response after 12 months (n = 21) had significantly lower outset levels of calculated free testosterone (fT) than in the nonresponders (n = 27). In the patients aged < 70 years (n = 13), both the fT and T values were lower than in the nonresponders (n = 15). There was no age difference between responders and nonresponders.
Conclusions:
TUMT did not influence hormone levels. These observations suggest that androgen status may influence the final result of treatment.