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Preejectional left ventricular wall motion in normal subjects using Doppler tissue imaging and correlation with
D Pellerin1, L Cohen, F Larrazet
1Department of Cardiology, University Hospital Bicêtre, Le Kremlin-Bicêtre, France.
The American Journal of Cardiology
|September 19, 1997
Summary
This study used Doppler tissue imaging to analyze left ventricular (LV) wall motion during the preejection period (PEP). Posterior wall inward motion velocities showed a significant correlation with LV ejection fraction (LVEF), suggesting clinical potential.
Area of Science:
- Cardiology
- Medical Imaging
- Physiology
Background:
- The preejection period (PEP) is related to left ventricular (LV) systolic function.
- Doppler tissue M-mode imaging allows measurement of myocardial wall velocities and motion direction changes.
Purpose of the Study:
- To measure septal and posterior preejectional intramyocardial velocities and durations.
- To correlate preejectional parameters with LV ejection fraction (LVEF).
Main Methods:
- Parasternal M-mode images of simultaneously recorded LV walls were digitized in 16 normal subjects.
- Subendocardial wall velocities were measured every 3.8 ms from the Q wave to the onset of ejection.
- Doppler tissue and flow traces were used to compare PEP duration.
Main Results:
- PEP duration did not differ between walls or techniques.
- Velocity reversals with mirror signs were observed in opposite walls.
- Strip 2 showed simultaneous early inward motion of both walls, with prolonged duration (p <0.0001).
- Peak velocities of strip 2 in the posterior wall positively correlated with LVEF (r = 0.71, p <0.006).
Conclusions:
- Posterior wall inward motion velocities during the preejection period may have clinical implications for assessing LV systolic function.
- Doppler tissue imaging provides valuable insights into LV preejectional wall mechanics.