Related Experiment Videos
Detection of pyramidal tract lesions in amyotrophic lateral sclerosis with magnetization-transfer measurements
Y Kato1, K Matsumura, Y Kinosada
1Department of Neurology, Mie University School of Medicine, Japan.
AJNR. American Journal of Neuroradiology
|September 20, 1997
Abstract
Purpose:
To determine the presence of small lesions in the pyramidal tract in patients with amyotrophic lateral sclerosis (ALS) by using magnetization-transfer (MT) measurements and MR imaging.
Methods:
MT ratios (MTRs) were measured in the posterior limb of the internal capsule in nine patients with ALS and in nine healthy volunteers.
Results:
The mean value of MTRs (%) in patients with ALS was 15.76 +/- 1.48, while that of the control subjects was 19.83 +/- 1.54. The difference was statistically significant.
Conclusions:
MT measurements are useful for detecting abnormalities associated with degeneration of the pyramidal tract in patients with ALS.