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Related Experiment Videos

Clarithromycin-induced digoxin intoxication

P Laberge1, P Martineau

  • 1Faculté de Pharmacie, Université de Montréal, Québec, Canada.

The Annals of Pharmacotherapy
|September 20, 1997
PubMed
Summary
This summary is machine-generated.

Clarithromycin can cause digoxin toxicity by affecting gut bacteria that metabolize the drug. Patients with kidney issues or high digoxin levels should be monitored closely when taking this antibiotic.

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Area of Science:

  • Pharmacology
  • Internal Medicine
  • Clinical Toxicology

Background:

  • Digoxin is a medication used to treat heart conditions.
  • Clarithromycin is an antibiotic that can interact with other drugs.
  • Intestinal metabolism of digoxin by Eubacterium lentum plays a role in its bioavailability.