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1,3-Dimethylpyrimidoheterocycles as antibacterial agents
H H Zoorob1, M Abou Elzahab, M Abdel-Mogib
1Faculty of Science, Al-Mansoura University, Chemistry Department, Egypt.
Arzneimittel-Forschung
|August 1, 1997
Abstract:
1,3-Dimethylbarbituric acid was used as a versatile precursor for the preparation of annelated pyranopyrimidines 2 and 3a-c besides pyrrolopyrimidine 12. The isolated pyrazolopyrimidines 8a-c and 10 and fused pyrazolopyrimidines 14a-d were also synthesized. In addition the new obtained pyrimidoheterocycles were subjected to bacterial testings.