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[Pathophysiologic and immunologic mechanisms of contrast medium-induced anaphylactoid immediate hypersensitivity--an
1Interdisziplinäres Therapiezentrum PsoriSol Klinik für Dermatologie und Allergologie, Hersbruck.
Abstract:
Since non-ionic radiocontrast media (RCM) have been introduced, the incidence of unwanted reactions has been significantly reduced in comparison to ionic compounds. However, acute anaphylactoid reactions with heterogenous symptoms within minutes after intravasal application are still a life-threatening risk of investigations with RCM. The present article summarizes the current view of the underlying pathomechanisms of such reactions.