[Pulmonary vagal afferents in man]
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Updated: Oct 31, 2026

Detection of G Protein-coupled Receptor Expression in Mouse Vagal Afferent Neurons using Multiplex In Situ Hybridization
Published on: September 20, 2021
1Ustav patologické fyziologie 2. lékarské fakulty UK, Praha.
Abstract:
Vagal afferentation from the lungs is mediated via various types of nerve fibers and is a prerequisite of numerous pulmonary reflexes. A review of studies on the morphology and functional examination of pulmonary vagal receptors is presented. Apart from the most frequently studied pulmonary stretch receptors also the role of irritant receptors and C-fibers is described. It is difficult to verify in man findings from animal experiments. Therefore, the studies testing the existence of pulmonary vagal reflexes in man are emphasised in the review. The importance of vagus nerves in cough, breathlessness, tachypnoea, in the control of the work of breathing and in the pattern of breathing is mentioned.
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