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Sudden death due to auto-immune Addison's disease in a 12-year-old girl
A M al Sabri1, N Smith, A Busuttil
1Forensic Medicine Unit, University of Edinburgh Medical School, Scotland.
International Journal of Legal Medicine
|January 1, 1997
Abstract:
A 12-year-old female suffering from adrenocortical insufficiency showed symptoms similar to a gastro-enteritis, and severe electrolytic and acid/base disturbances which progressed into cerebral oedema and death. Autopsy findings included depletion of the adrenal cortex, with enlargement and eosinophilia of surviving cells. In ante-mortem blood, anti-adrenal auto-antibodies were found and elevated levels of ACTH and cortisol with a low level of aldosterone.