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Xanthomatous posterior pyramid meningioma in a 2-year-old girl
A Germanò1, S Galatioto, G La Rosa
1Neurosurgical Clinic, University of Messina, Italy.
Abstract:
Meningiomas are common lesions in adults but unusual in infancy and meningiomas located in the posterior cranial fossa are even more rare. Metaplastic changes of meningothelial meningiomas can lead to the rarely observed xanthomatous form. We describe the case of a posterior pyramid xanthomatous meningioma in a 2-year-old girl. After detailed neuroradiological evaluation, the histological diagnosis was confirmed with the aid of immunohistochemical evaluation. A critical case evaluation in the light of the more recent literature, the surgical strategy and technique, and an immunohistological hypothesis are reported.
Insights
This study reports a rare case of xanthomatous meningioma in a 2-year-old child. The posterior cranial fossa tumor was diagnosed using advanced imaging and immunohistochemistry.
Area of Science:
- Neuro-oncology
- Pediatric Pathology
- Neurosurgery
Background:
- Meningiomas are common in adults but rare in infants.
- Posterior cranial fossa meningiomas are exceptionally rare in children.
- Xanthomatous changes represent a rare metaplastic form of meningothelial meningiomas.