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Perspectives in pancreatic pain

A S Salim1

  • 1Department of Surgery, National University of Malaysia, Jalan Raja Muda, Kuala Lumpur, Malaysia.

HPB Surgery : a World Journal of Hepatic, Pancreatic and Biliary Surgery
|January 1, 1997
PubMed
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This review covers pain mechanisms in chronic pancreatitis and details medical and surgical treatments for pain management. It explores key factors contributing to pain in this condition.

Area of Science:

  • Gastroenterology
  • Pain Medicine
  • Surgical Science

Background:

  • Chronic pancreatitis is a debilitating condition characterized by persistent abdominal pain.
  • Understanding the underlying mechanisms of pain is crucial for effective management.
  • Current treatment strategies often involve a multimodal approach.

Purpose of the Study:

  • To review the key mechanisms implicated in the causation of pain in chronic pancreatitis.
  • To describe established and emerging medical and surgical techniques for managing chronic pancreatitis pain.

Main Methods:

  • Comprehensive literature review of studies on chronic pancreatitis pain mechanisms.
  • Analysis of clinical guidelines and research on pain treatment modalities.
  • Synthesis of information on both pharmacological and interventional approaches.

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Main Results:

  • Pain in chronic pancreatitis is multifactorial, involving neuropathic, inflammatory, and mechanical components.
  • Medical management includes analgesics, nerve blocks, and endoscopic therapies.
  • Surgical options range from denervation procedures to pancreatic resection.

Conclusions:

  • Effective pain management in chronic pancreatitis requires a thorough understanding of its complex mechanisms.
  • A combination of medical and surgical interventions offers the best outcomes for patients.
  • Further research into novel therapeutic targets is warranted.