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Related Experiment Videos

Persistent hyperammonemia in two related Morgan weanlings

R S McCornico1, W M Duckett, P A Wood

  • 1Department of Food Animal and Equine Medicine, North Carolina State University, College of Veterinary Medicine, Raleigh, USA.

Journal of Veterinary Internal Medicine
|July 1, 1997
PubMed
Summary

Two young horses developed persistent hyperammonemia, a condition of high blood ammonia. Diagnostic tests suggested a possible inherited disorder, hyperornithinemia, hyperammonemia, and homocitrullinuria (HHH) syndrome, due to a defective urea cycle enzyme.

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Area of Science:

  • Veterinary Medicine
  • Biochemistry
  • Genetics

Background:

  • Persistent hyperammonemia in young horses can be challenging to diagnose.
  • Previous evaluations ruled out common toxic, developmental, or infectious causes.