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[Three cases of recombinated gene in the ABO blood group system]
1Department of Forensic Medicine, Yamagata University School of Medicine, Japan.
Nihon Hoigaku Zasshi = the Japanese Journal of Legal Medicine
|June 1, 1997
Abstract:
We found the AG allele in three cases (two cases are AGOA type and one case is A1AG type) out of unrelated 150 Japanese by amplified product length polymorphism technique for genotyping of ABO blood group system. The AG alleles amplified with allele-specific PCR method, were analyzed from exon 6 to 7 by direct sequencing. The AG allele was divided into suballees, AG1 and AG2. The AG1 and AG2 were revealed to have the same sequence as B allele in exon 6. In exon 7, however, the AG1 allele had the same sequence as A1 allele and the AG2 allele had hybrid sequence of B and OG allele.