Related Experiment Video
Updated: Aug 18, 2026

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
Published on: March 14, 2017
[Methods of preoperative hemodilution to reduce homologous blood transfusion]
1Department of Anesthesiology, School of Medicine, National Defence Medical College.
Many problems arise from homologous blood transfusion in operative patients. The virtues include reduced likelihood of reactions to transfused blood and reduction or elimination of the risk of alloimmunization and transfusion transmitted diseases such as hepatitis C and the human immunodeficiency virus. Provided that skillful surgical technique is applied and the use of blood products is restricted, autologous transfusion techniques (predonation of autologous blood, preoperative plasmapheresis, acute normovolemic hemodilution, and intra- and postoperative blood salvage) can be performed with an acceptable risk for patients. Preoperative collection of blood with hemodilution is a simple method to allow autologous blood transfusion. To have recourse to apheresis techniques allows to increase the number of autologous transfused patients.
Many problems arise from homologous blood transfusion in operative patients. The virtues include reduced likelihood of reactions to transfused blood and reduction or elimination of the risk of alloimmunization and transfusion transmitted diseases such as hepatitis C and the human immunodeficiency virus. Provided that skillful surgical technique is applied and the use of blood products is restricted, autologous transfusion techniques (predonation of autologous blood, preoperative plasmapheresis, acute normovolemic hemodilution, and intra- and postoperative blood salvage) can be performed with an acceptable risk for patients. Preoperative collection of blood with hemodilution is a simple method to allow autologous blood transfusion. To have recourse to apheresis techniques allows to increase the number of autologous transfused patients.
More Related Videos
05:25Preservation of Porcine Donation after Circulatory Death (DCD) Liver by Perfusion and Orthotopic Liver Transplantation
Published on: June 14, 2024
09:47Exploring Alternative Perfusion Solutions Using Next-Generation Polymerized Hemoglobin-Based Oxygen Carriers in a Model of Rat Ex Vivo Lung Perfusion
Published on: June 14, 2024
Related Concept Videos
Blood Transfusion and Agglutination
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
Blood Transfusion
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
Kidney Transplant II: Surgical Procedure