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Enteral nutrition after bone marrow transplantation
A Papadopoulou1, A MacDonald, M D Williams
1Institute of Child Health, University of Birmingham.
Archives of Disease in Childhood
|August 1, 1997
Summary
Enteral nutrition effectively limits nutritional depletion after bone marrow transplantation (BMT) when tolerated. Close monitoring of nutritional biochemistry is crucial for timely supplementation in BMT patients.
Area of Science:
- Pediatric Hematology
- Gastroenterology
- Nutritional Science
Background:
- Nutritional management post-bone marrow transplantation (BMT) is complex.
- Enteral nutrition (EN) is cost-effective but its efficacy post-BMT is unclear.
Purpose of the Study:
- To assess the tolerance and effectiveness of nasogastric enteral nutrition in children post-BMT.
- To compare nutritional status, wellbeing, and biochemistry between EN and dietetic advice groups.
Main Methods:
- Prospective assessment of 21 children receiving nasogastric EN and 8 children receiving dietetic advice post-BMT.
- Evaluation of nutritional status, wellbeing, and biochemical parameters.
Main Results:
- The EN group showed greater improvements in weight and mid-upper arm circumference.
- Fever and positive blood cultures were more frequent in the dietetic advice group.
- Diarrhea during EN was not linked to fat malabsorption; carbohydrate malabsorption occurred only with rotavirus.
Conclusions:
- Enteral nutrition, when tolerated, is effective in mitigating nutritional insult following BMT.
- Nutritional biochemistry requires close monitoring for supplementation needs in BMT patients.