[Late clinical results of prosthetic valve replacement undergone more than ten years ago]

We evaluated late clinical results of 207 hospital survivors, who underwent prosthetic valve replacement from Dec. 1965 to May 1979 for acquired valvular heart diseases. The study group consisted of 134 patients with MVR (46 S-E non cloth covered (SENM), 56 S-E cloth covered (SECM), 16 Björk-Shiley (BSM), 16 Carpentier-Edwads (CEM)), 47 with AVR (21 S-E non cloth covered (SENA), 15 S-E cloth covered (SECA), 11 Björk-Shiley (BSA)) and 26 with combined aortic and mitral valve replacement using S-E non cloth and/or cloth covered ball valves. Actuarial analysis (Kaplan-Meier) revealed ten year survival rate was 85.1 +/- 5.6% in SENM, 77.1 +/- 5.8% in SECM, 85.7 +/- 9.4% in BSM, 77.8 +/- 11.4% in CEM, 79.2 +/- 9.3% in SENA, 71.8 +/- 12.0% in SECA, 90.9 +/- 8.7% in BSA and 53.1 +/- 10.4% in combined valve replacement group. Survival rate of combined valve replacement group was significantly lower than other groups (p < 0.05). Also, ten year reoperation free rate was 100% in BSM and BSA, 87.1 +/- 5.4% in SENM, 91.3 +/- 4.2% in SECM, 61.5 +/- 13.5% in CEM, 90.2 +/- 6.6% in SENA and 77.1 +/- 11.7% in SECA. Reoperation free rate of CEM group was significantly lower than other mitral groups (p < 0.05). Immature cardiac protection during anoxic arrest and unestablished anticoagulant therapy for implanted prosthetic valves in those days might increased mortality and morbidity in S-E groups.