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[Use of medicines by children attending nursery schools]
1Intituto da Criança do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Brasil.
Insights
Children frequently received multiple medications, with younger children using more drugs. Inappropriate prescriptions, including antibiotics and unapproved medications, were common, highlighting a need for improved pediatric prescribing practices.
Area of Science:
- Pediatric Pharmacology
- Drug Utilization Studies
- Public Health
Context:
- A 2-month follow-up study involving 1,382 children across 15 day-care centers in Pinheiros, São Paulo, Brazil.
- Investigated medication patterns in a pediatric population within a specific urban setting.
Purpose:
- To analyze the patterns of medicine use among children attending day-care centers.
- To identify the types of medications prescribed and assess the appropriateness of their use in pediatric patients.
Summary:
- 37% of children received 1,409 drugs, with an average of 50.9 medicines per 100 children/month.
- Younger children (0-2 years) used more medications than older children (2-7 years).
- Anti-infectives, respiratory drugs, and antipyretics were most common; many prescriptions were inappropriate, including excessive antibiotics (66%) and unapproved medications.
Impact:
- Highlights significant issues in pediatric prescribing, including overuse of antibiotics and inappropriate therapies for common childhood illnesses.
- Suggests a need for enhanced physician education and stricter guidelines for medication use in children.
- Underscores potential risks associated with the use of unapproved or questionable medications in pediatric populations.
Abstract:
In order to study the pattern of the use of medicines by children, 1,382 children seen at 15 of the 16 day-care centers of Pinheiros, S. Paulo city (SP) (Brasil), were followed-up for 2 months. Of these, 37% received 1,409 drugs. Average drug use was 50.9 medicines/100 children/month and the number of medicines used by each child ranged from 0 to 13. Younger children (0-2 years) received more medicines and more frequently than older children; over 80% of the younger children received one or more medicines, and more than 20% received 5 or more medicines vs. less than 45% and 5%, respectively, in the group of children aged 2-7 years. The medications most frequently employed were anti-infective, respiratory medicines and antipyretics used by, respectively. 20.1%, 19.0% and 14.0% of the children studied (usually for respiratory problems). Physicians prescribed 93% of medicines, but there were many inappropriate therapies for benign conditions, such as bronchitis and common colds. Antibiotic measure was observed (66%) including an excessive number of cloramphenicol prescriptions. Also, there were many prescriptions of doubtful value (decongestants, expectorants, vitamin and mineral supplements) and usage of as yet un approved medications for children (diclofenac, benzidamin, iodides).
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