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In vitro activity of trovafloxacin against Chlamydia pneumoniae
P M Roblin1, A Kutlin, M R Hammerschlag
1Department of Pediatrics, State University of New York Health Science Center at Brooklyn, 11203, USA.
Antimicrobial Agents and Chemotherapy
|September 26, 1997
Abstract:
The in vitro susceptibilities of 12 strains of Chlamydia pneumoniae to a new quinolone, trovafloxacin, and ofloxacin, doxycycline, erythromycin, and azithromycin were determined. The activity of trovafloxacin was similar to that of ofloxacin, with a MIC at which 90% of the isolates are inhibited and a minimal concentration at which 90% of the isolates are killed of 1.0 microg/ml, but trovafloxacin was less active than doxycycline, erythromycin, and azithromycin.