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[Polymorphism and clinical significance of human paraoxonase enzyme]
1Haynal Imre Egészségtudományi Egyetem, I. Belgyógyászati Klinika, Budapest.
Orvosi Hetilap
|August 17, 1997
Abstract:
The human serum paraoxonase (PON) in one of the enzymes showing pharmacogenetic polymorphism. According to our present knowledge the enzyme inhibits the lipidperoxydation and through its effect on the lipid metabolism or another pathogenetic mechanism may take part in the pathogenesis of diabetes mellitus and ishaemic heart disease.