Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Epithelial nephrogenesis

M Horster1, S Huber, J Tschöp

  • 1Physiologisches Institut der Universität München, Pettenkoferstr. 12, D-80336 München, Germany.

Pflugers Archiv : European Journal of Physiology
|November 5, 1997
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Distinct Skin Penetration and Immune Responses to Ionic and Nanoparticulate Cobalt in Allergic Contact Dermatitis.

Allergy·2026
Same author

High-Statistics Measurement of Collins and Sivers Asymmetries for Transversely Polarized Deuterons.

Physical review letters·2024
Same author

Final COMPASS Results on the Transverse-Spin-Dependent Azimuthal Asymmetries in the Pion-Induced Drell-Yan Process.

Physical review letters·2024
Same author

Serological indication of chronic inflammatory demyelinating polyneuropathy as an extrahepatic manifestation of hepatitis E virus infection.

Scientific reports·2024
Same author

[Five case reports on granulosa cell tumors in cattle with practical information on diagnosis and possible progression].

Schweizer Archiv fur Tierheilkunde·2024
Same author

Consistency of convolutional neural networks in dermoscopic melanoma recognition: A prospective real-world study about the pitfalls of augmented intelligence.

Journal of the European Academy of Dermatology and Venereology : JEADV·2023
Same journal

Expression of protein kinase A catalytic subunits in healthy and diseased mouse kidneys.

Pflugers Archiv : European journal of physiology·2026
Same journal

Localization of O₂‑sensing ADO‑RGS pathway components in mouse and human kidneys under normoxia, hypoxia and renal fibrosis.

Pflugers Archiv : European journal of physiology·2026
Same journal

Cholesterol-depleting dextrin depolarizes sarcolemma: the contribution of sodium / calcium channels and membrane integrity.

Pflugers Archiv : European journal of physiology·2026
Same journal

Inhibition of (interstitial) P2Y<sub>6</sub> receptors attenuates fibrosis progression.

Pflugers Archiv : European journal of physiology·2026
Same journal

Renal NHE3 is required to limit hypokalemia and metabolic acidosis during dietary potassium deficiency.

Pflugers Archiv : European journal of physiology·2026
Same journal

Xenin-25 improves indomethacin-induced acute gastric injury in rats.

Pflugers Archiv : European journal of physiology·2026
See all related articles

Kidney development involves inductive signaling between the metanephric mesenchyme and ureteric bud. This process drives nephrogenesis, forming the nephron and collecting duct system through cell conversion and branching morphogenesis.

Area of Science:

  • Developmental biology
  • Renal embryology
  • Cellular biology

Background:

  • The definitive kidney (metanephros) arises from the metanephric mesenchymal blastema and the ureteric bud.
  • These embryonic tissues undergo inductive signaling crucial for kidney formation.
  • Nephrogenesis serves as a model for studying fundamental developmental processes.

Purpose of the Study:

  • To review cellular and extracellular events during epithelial metanephrogenesis.
  • To highlight key developmental processes exemplified by kidney formation.
  • To synthesize current understanding of inductive interactions in kidney development.

Main Methods:

  • Review of existing literature on kidney development.
  • Analysis of cellular and extracellular events.

Related Experiment Videos

  • Focus on mesenchyme-to-epithelium transition and branching morphogenesis.

    • Main Results:

    • Mesenchymal cells aggregate, convert to epithelium, and differentiate into nephron cell populations.
    • The ureteric bud undergoes branching morphogenesis to form the collecting duct system.
    • Key developmental processes studied include inductive signaling, cell lineage, polarization, and gene expression.

    Conclusions:

    • Epithelial metanephrogenesis is a complex process driven by inductive interactions.
    • Understanding kidney development provides insights into broader developmental biology principles.
    • Further research on cellular and extracellular events is essential for a complete picture of nephrogenesis.