Related Experiment Video
Updated: Aug 11, 2026
Morphological and Functional Assessment of the Right Ventricle Using 3D Echocardiography
Published on: October 28, 2020
Regional right ventricular endocardial motion in normal hearts and in hearts with left ventricular aneurysm: a three
1Julius Silver Institute, Department of Biomedical Engineering, Technion-Israel Institute of Technology, Haifa, Israel.
Insights
Left ventricular aneurysm alters right ventricular motion, causing apical abnormalities compensated by increased basal motion. This study developed a 3D method to measure regional right ventricular motion in normal and diseased hearts.
Area of Science:
- Cardiovascular Imaging
- Cardiac Mechanics
- Medical Physics
Background:
- Right ventricular (RV) motion is crucial for cardiac function.
- Left ventricular (LV) aneurysm can impact RV performance.
- Accurate assessment of RV regional motion is challenging.
Purpose of the Study:
- To develop and validate a 3D method for assessing regional RV motion.
- To compare RV motion patterns in normal subjects versus patients with LV aneurysm.
- To investigate the effects of LV aneurysm on RV systolic function.
Main Methods:
- Three-dimensional (3D) reconstruction of the RV from Cine-CT data.
- Endocardial border tracing to define RV geometry.
- 3D stroke-volume-element analysis to quantify regional RV systolic motion.
- Comparison of motion patterns between normal controls and LV aneurysm patients.
Main Results:
- Normal RV exhibits greater posterior than anterior endocardial motion without longitudinal gradient.
- LV aneurysm is associated with altered RV motion, specifically increased longitudinal systolic motion from apex to base.
- A significant RV motion abnormality at the apex was observed in LV aneurysm patients, compensated by increased basal motion.
Conclusions:
- A novel 3D method effectively quantifies regional RV motion.
- LV aneurysm significantly impacts RV regional systolic function.
- RV motion abnormalities in LV aneurysm are characterized by apical dysfunction and basal compensation.
Abstract:
We mapped the three dimensional (3D) regional right ventricular (RV) motion using Cine-CT in 9 normal subjects and compared it to data from 10 patients with left ventricular (LV) aneurysm. The endocardial borders were traced and the RV's reconstructed in 3D. Regional perpendicular RV systolic motion was evaluated by our 3D stroke-volume-element approach, and the circumferential and longitudinal variations determined. The normal RV is characterized by higher endocardial motion in the posterior relative to the anterior regions (p < 0.0001), and no longitudinal (apex-to-base) gradient. In hearts with LV aneurysms, similar circumferential variations in wall motion are accompanied with a longitudinal increase in systolic motion, from apex to the base (p < 0.0001). Therefore, a 3D method for measurement of RV regional motion was developed and applied to normal and LV aneurysm patients, showing that LV aneurysm causes RV motion abnormality at the apex, compensated by an increased basal motion.
More Related Videos
08:10Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation
Published on: July 20, 2022
07:38Comprehensive Echocardiographic Assessment of Right Ventricle Function in a Rat Model of Pulmonary Arterial Hypertension
Published on: January 20, 2023