Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Robust and sensitive nylon hybridization membrane suitable for high-throughput robotic arraying applications.

BioTechniques·2002
Same author

Chemistry of coordinated nitroxyl. Reagent-specific protonations of trans-Re(CO)(2)(NO)(PR(3))(2) (R = Ph, Cy) that give the neutral nitroxyl complexes cis,trans-ReCl(CO)(2)(NH=O)(PR(3))(2) or the cationic hydride complex [trans,trans-ReH(CO)(2)(NO)(PPh(3))(2)(+)][SO(3)CF(3)(-)].

Inorganic chemistry·2001
Same author

The structure and spin coupling of catalase compound I: a study of noncovalent effects.

Journal of the American Chemical Society·2001
Same author

Rational design, synthesis, and biological activity of benzoxazinones as novel factor Xa inhibitors.

Journal of medicinal chemistry·2000
Same author

[Color Doppler imaging of central retinal artery in retinopathy of prematurity].

Harefuah·2000
Same author

Structural basis of the thrombin selectivity of a ligand that contains the constrained arginine mimic (2S)-2-amino-(3S)-3-(1-carbamimidoyl- piperidin-3-yl)-propanoic acid at P1.

Journal of medicinal chemistry·2000

Related Experiment Video

Updated: Jul 17, 2026

Three Different Protocols of Corneal Collagen Crosslinking in Keratoconus: Conventional, Accelerated and Iontophoresis
07:29

Three Different Protocols of Corneal Collagen Crosslinking in Keratoconus: Conventional, Accelerated and Iontophoresis

Published on: November 12, 2015

Unilateral keratoconus. Incidence and quantitative topographic analysis

D R Holland1, N Maeda, S B Hannush

  • 1Department of Ophthalmology, University of Texas Southwestern Medical Center at Dallas, USA.

Ophthalmology
|October 6, 1997
PubMed
Summary

Unilateral keratoconus is rare, with most cases eventually progressing to affect both eyes. Quantitative topography measures show no difference between unilateral and bilateral keratoconus, advising caution with refractive surgery on the unaffected eye.

More Related Videos

Full-Field Optical Coherence Microscopy for Histology-Like Analysis of Stromal Features in Corneal Grafts
07:51

Full-Field Optical Coherence Microscopy for Histology-Like Analysis of Stromal Features in Corneal Grafts

Published on: October 21, 2022

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
06:15

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

Related Experiment Videos

Last Updated: Jul 17, 2026

Three Different Protocols of Corneal Collagen Crosslinking in Keratoconus: Conventional, Accelerated and Iontophoresis
07:29

Three Different Protocols of Corneal Collagen Crosslinking in Keratoconus: Conventional, Accelerated and Iontophoresis

Published on: November 12, 2015

Full-Field Optical Coherence Microscopy for Histology-Like Analysis of Stromal Features in Corneal Grafts
07:51

Full-Field Optical Coherence Microscopy for Histology-Like Analysis of Stromal Features in Corneal Grafts

Published on: October 21, 2022

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
06:15

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

Area of Science:

  • Ophthalmology
  • Corneal topography
  • Keratoconus research

Background:

  • Keratoconus is a progressive corneal ectasia.
  • Unilateral presentation of keratoconus is uncommon.
  • Understanding disease progression is crucial for patient management.

Purpose of the Study:

  • To determine the incidence of unilateral keratoconus.
  • To compare corneal topography metrics between unilateral and bilateral keratoconus.
  • To inform clinical decision-making regarding refractive surgery.

Main Methods:

  • Retrospective analysis of 164 patients with moderate-to-advanced keratoconus.
  • Corneal topography evaluated in both eyes.
  • Comparison of Keratoconus Prediction Index (KPI), Surface Asymmetry Index (SAI), and Surface Regularity Index (SRI).

Main Results:

  • Only 1.83% of patients presented with unilateral keratoconus.
  • No significant differences in KPI, SAI, or SRI between unilateral and bilateral cases.
  • One patient initially diagnosed with unilateral keratoconus developed contralateral signs over 4 years.

Conclusions:

  • The incidence of clinically diagnosed unilateral keratoconus is very low.
  • Quantitative topographic descriptors are similar in unilateral and bilateral keratoconus.
  • Contralateral eyes of unilateral keratoconus patients may develop the condition over time, cautioning against refractive surgery.