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Iliac artery stenosis measurements: comparison of two-dimensional time-of-flight and three-dimensional dynamic
E Poon1, E K Yucel, H Pagan-Marin
1Department of Radiology, Boston Medical Center, MA 02118, USA.
Objective:
We compared our ability to make iliac artery measurements on two-dimensional (2D) time-of-flight (TOF) and three-dimensional dynamic gadolinium-enhanced MR angiography with conventional angiography.
Subjects And Methods:
Fifteen patients with lower extremity vascular disease underwent pelvic MR angiography. Parameters of the cardiac-gated axial 2D TOF sequence included a TR/TE of 24/7 msec and a 50 degrees flip angle. Parameters for the three-dimensional MR angiography sequence, in which we obtained 32 coronal 3-mm slices with fat suppression, included a TR/TE of 32/5 msec and a 40 degrees flip angle during infusion of 40 ml of gadolinium-chelated contrast material. Patients then underwent conventional angiography of the iliac arteries. Maximum stenosis in the common iliac, external iliac, and common femoral arteries was then measured. Measurements of stenosis were compared by repeated measures of analysis of variance. Sensitivity and specificity were calculated for identification of greater than or equal to 50% stenosis and less than 50% stenosis.
Results:
For all vessels studied, we found no significant difference in measurements obtained from the gadolinium-enhanced MR angiography technique and those obtained from conventional angiography (p > .05). However, significantly different stenotic measurements were obtained from the 2D TOF MR angiography sequence and conventional angiography. In the external iliac arteries, 2D TOF MR angiography exaggerated stenoses most substantially. Gadolinium-enhanced MR angiography achieved 100% sensitivity and specificity.
Conclusion:
Dynamic gadolinium-enhanced MR angiography was more accurate than 2D TOF MR angiography when measuring degree of stenosis in the iliac arteries.
Insights
Dynamic gadolinium-enhanced MR angiography accurately measures iliac artery stenosis, outperforming 2D TOF MR angiography. This technique offers superior results for assessing vascular disease.
Area of Science:
- Radiology
- Medical Imaging
- Vascular Disease Assessment
Background:
- Accurate measurement of iliac artery stenosis is crucial for managing lower extremity vascular disease.
- Conventional angiography is the standard, but non-invasive imaging techniques are continually being evaluated.
Purpose of the Study:
- To compare the accuracy of two-dimensional (2D) time-of-flight (TOF) MR angiography and three-dimensional dynamic gadolinium-enhanced MR angiography with conventional angiography for iliac artery stenosis measurements.
Main Methods:
- Fifteen patients with lower extremity vascular disease underwent pelvic MR angiography (2D TOF and 3D dynamic gadolinium-enhanced) and conventional angiography.
- Stenosis in the common iliac, external iliac, and common femoral arteries was measured and compared between techniques.
Main Results:
- No significant difference was found between gadolinium-enhanced MR angiography and conventional angiography (p > .05).
- 2D TOF MR angiography yielded significantly different stenotic measurements compared to conventional angiography, particularly exaggerating stenosis in external iliac arteries.
- Gadolinium-enhanced MR angiography demonstrated 100% sensitivity and specificity.
Conclusions:
- Dynamic gadolinium-enhanced MR angiography is more accurate than 2D TOF MR angiography for measuring iliac artery stenosis.
- Gadolinium-enhanced MR angiography provides a reliable, non-invasive alternative for evaluating iliac artery disease.