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Renal artery repair in African-Americans
J S Deitch1, K J Hansen, T E Craven
1Department of General Surgery, Wake Forest University Medical Center, Winston-Salem, North Carolina 27157-1095, USA.
Journal of Vascular Surgery
|October 6, 1997
Summary
African-Americans with hypertension showed favorable blood pressure and renal function improvements after atherosclerotic renal artery (RA) repair. These positive outcomes in RA disease treatment were similar to those seen in Caucasian patients.
Area of Science:
- Vascular Surgery
- Nephrology
- Hypertension Management
Background:
- Atherosclerotic renovascular disease affects blood supply to kidneys.
- Hypertension is a common comorbidity, especially in African-Americans.
- Renal artery repair is a treatment option for renovascular hypertension.
Purpose of the Study:
- To evaluate outcomes of atherosclerotic renal artery repair in African-Americans.
- To compare these outcomes with Caucasian patients undergoing similar procedures.
- To assess the impact on blood pressure and renal function.
Main Methods:
- Retrospective review of 485 patients undergoing renal artery repair (1987-1996).
- Comparison of 28 African-Americans with 370 Caucasians based on clinical data.
- Analysis of preoperative/postoperative blood pressure, renal function, and survival.
Main Results:
- African-Americans had higher rates of heart disease and tended towards more severe renal dysfunction pre-operatively.
- 74% of African-American patients experienced improved hypertension post-repair.
- Mean estimated glomerular filtration rate improved significantly (34 to 42 ml/min/1.73 m2).
- Outcomes in African-Americans were comparable to Caucasians.
Conclusions:
- Operative renal artery repair yields favorable blood pressure and renal function responses in selected African-Americans.
- Clinical benefits observed in African-Americans are similar to those in Caucasian patients.
- Supports screening hypertensive African-Americans for renal artery disease.