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Cerebral primitive neuro-ectodermal tumour following treatment of a unilateral retinoblastoma
G Dorfmüller1, F G Würtz, R Kleinert
1Clinic of Neurosurgery, Klagenfurt, Austria.
Acta Neurochirurgica
|January 1, 1997
Abstract:
Cerebral primitive neuro-ectodermal tumour (PNET) occurring as a second primary malignancy in childhood is exceedingly rare. We present a 7-year-old boy who developed a proven supratentorial PNET five years after enucleation and radio-/chemotherapy for a sporadic, unilateral retinoblastoma with optic nerve invasion. The association with this malignant eye disease as well as the effect of irradiation and multi-agent chemotherapy on second tumour induction are evaluated.