The D3 dopamine receptor: neurobiology and potential clinical relevance

Fish oil improves motor function, limits blood-brain barrier disruption, and reduces Mmp9 gene expression in a rat model of juvenile traumatic brain injury.

Prostaglandins, leukotrienes, and essential fatty acids·2013

The dopamine D3/D2 agonist (+)-PD-128,907 [(R-(+)-trans-3,4a,10b-tetrahydro-4-propyl-2H,5H-[1]benzopyrano[4,3-b]-1,4-oxazin-9-ol)] protects against acute and cocaine-kindled seizures in mice: further evidence for the involvement of D3 receptors.

The Journal of pharmacology and experimental therapeutics·2008

C57BL/6J mice exhibit reduced dopamine D3 receptor-mediated locomotor-inhibitory function relative to DBA/2J mice.

Neuroscience·2006

Protection against cocaine toxicity in mice by the dopamine D3/D2 agonist R-(+)-trans-3,4a,10b-tetrahydro-4-propyl-2H,5H-[1]benzopyrano[4,3-b]-1,4-oxazin-9-ol [(+)-PD 128,907].

The Journal of pharmacology and experimental therapeutics·2004

Modulation of [3H]quinpirole binding at striatal D2 dopamine receptors by a monoamine oxidaseA-like site: evidence from radioligand binding studies and D2 receptor- and MAO(A)-deficient mice.

Life sciences·2002

D(3) dopamine receptors in rat spinal cord: implications for sensory and motor function.

Neuroscience letters·2001

Application of human liver cell models in drug development and toxicity studies: The role of membrane transporters.

Pharmacological reviews·2026

The skeletal connectome: From molecular circuitry to systemic network medicine.

Pharmacological reviews·2026

Hunting gremlins: GREM1 as a new therapeutic target for multiple diseases including glaucoma.

Pharmacological reviews·2026

Peptide hormone-based combinational pharmacotherapies for chronic metabolic diseases.

Pharmacological reviews·2026

Chronic pain in Alzheimer disease and the role of neuroimmune interactions.

Pharmacological reviews·2026

Renal aging and associated diseases: Common mechanisms and therapeutic approaches.

Pharmacological reviews·2026

High levels of nitric oxide and peroxynitrite with protein nitration: a new therapeutic target for gliomas.

Medical gas research·2026

Systematic Analysis of Stromal-Epithelial Crosstalk Reveals the FGF21-FGFR3 Axis as a Key Driver of Corneal Wound Healing.

Investigative ophthalmology & visual science·2026

CACNA1C Genetic Variants Differentially Affect Neuronal Networks Through Divergent Pathways.

Biological psychiatry global open science·2026

Localized disruption of the presynaptic endoplasmic reticulum in Atlastin mutants.

Journal of cell science·2026

PET-MRI effects of N-acetylcysteine in patients with multiple sclerosis.

IBRO neuroscience reports·2026

Genome-wide CRISPRi screen in human iNeurons identifies novel negative mTOR regulator genes associated with focal cortical dysplasia.

Neurobiology of disease·2026

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The D3 dopamine receptor: neurobiology and potential clinical relevance

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Fish oil improves motor function, limits blood-brain barrier disruption, and reduces Mmp9 gene expression in a rat model of juvenile traumatic brain injury.

The dopamine D3/D2 agonist (+)-PD-128,907 [(R-(+)-trans-3,4a,10b-tetrahydro-4-propyl-2H,5H-[1]benzopyrano[4,3-b]-1,4-oxazin-9-ol)] protects against acute and cocaine-kindled seizures in mice: further evidence for the involvement of D3 receptors.

C57BL/6J mice exhibit reduced dopamine D3 receptor-mediated locomotor-inhibitory function relative to DBA/2J mice.

Protection against cocaine toxicity in mice by the dopamine D3/D2 agonist R-(+)-trans-3,4a,10b-tetrahydro-4-propyl-2H,5H-[1]benzopyrano[4,3-b]-1,4-oxazin-9-ol [(+)-PD 128,907].

Modulation of [3H]quinpirole binding at striatal D2 dopamine receptors by a monoamine oxidaseA-like site: evidence from radioligand binding studies and D2 receptor- and MAO(A)-deficient mice.

D(3) dopamine receptors in rat spinal cord: implications for sensory and motor function.

Application of human liver cell models in drug development and toxicity studies: The role of membrane transporters.

The skeletal connectome: From molecular circuitry to systemic network medicine.

Hunting gremlins: GREM1 as a new therapeutic target for multiple diseases including glaucoma.

Peptide hormone-based combinational pharmacotherapies for chronic metabolic diseases.

Chronic pain in Alzheimer disease and the role of neuroimmune interactions.

Renal aging and associated diseases: Common mechanisms and therapeutic approaches.

High levels of nitric oxide and peroxynitrite with protein nitration: a new therapeutic target for gliomas.

Systematic Analysis of Stromal-Epithelial Crosstalk Reveals the FGF21-FGFR3 Axis as a Key Driver of Corneal Wound Healing.

CACNA1C Genetic Variants Differentially Affect Neuronal Networks Through Divergent Pathways.

Localized disruption of the presynaptic endoplasmic reticulum in Atlastin mutants.

PET-MRI effects of N-acetylcysteine in patients with multiple sclerosis.

Genome-wide CRISPRi screen in human iNeurons identifies novel negative mTOR regulator genes associated with focal cortical dysplasia.

Related Experiment Videos

The D3 dopamine receptor: neurobiology and potential clinical relevance

Related Concept Videos

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