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Hypersensitivity reactions to cisplatin following multiple uncomplicated courses: a report on two cases
Y Onoyama1, T Umezu, Y Kuriaki
1Department of Obstetrics and Gynecology, Matsuyama Red Cross Hospital, Ehime, Japan.
The Journal of Obstetrics and Gynaecology Research
|August 1, 1997
Abstract:
Two patients with ovarian cancer who had received multiple courses of cisplatin without complications experienced hypersensitivity reactions to cisplatin: one, involving intrahepatic artery infusion, manifested general erythema, dyspnea, and hypotension; the other, involving intravenous infusion, manifested abdominal pain, general erythema, and fever. When platinum-containing agents are administered, patients should be closely monitored for hypersensitivity reactions, even in previously uncomplicated cases.