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Published on: May 22, 2021
Cysticercosis of the brain in dogs in México City
Abstract:
In a study of 150 dogs with neurologic disorders, on the prevalence and location of Cysticercus cellulosae, 3 (2%) were parasitized and several C cellulosae were located in subarachnoid spaces, cerebral cortex, white matter, and ventricles of the brain. A chronic inflammatory exudate was found in host tissues surrounding the parasites. Unlike human infected brains, basal granulomatous inflammation or Cysticercus racemosus were not found in the canine brain tissues.
Insights
Cysticercus cellulosae infection in dogs is rare, affecting 2% of those with neurologic disorders. Parasites were found in various brain locations, causing inflammation but differing from human infections.
Area of Science:
- Veterinary Neurology
- Parasitology
- Canine Pathology
Background:
- Neurologic disorders are common in dogs.
- Cysticercus cellulosae is a parasitic infection that can affect the central nervous system.
Purpose of the Study:
- To determine the prevalence and location of Cysticercus cellulosae in dogs with neurologic disorders.
- To characterize the host tissue response to Cysticercus cellulosae in the canine brain.
Main Methods:
- Post-mortem examination of 150 dogs with diagnosed neurologic disorders.
- Histopathological analysis of brain tissues to identify parasites and inflammatory responses.
Main Results:
- Prevalence of Cysticercus cellulosae infection was 2% (3 out of 150 dogs).
- Parasites were identified in the subarachnoid spaces, cerebral cortex, white matter, and ventricles.
- A chronic inflammatory exudate surrounded the parasites in host tissues.
- Absence of basal granulomatous inflammation and Cysticercus racemosus, distinguishing canine from human infections.
Conclusions:
- Cysticercus cellulosae is an uncommon cause of neurologic disease in dogs.
- The location and host response differ from those observed in human cysticercosis.
- Further research may elucidate the specific pathogenesis in canine neurocysticercosis.
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