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[Hemocompatibility of various synthetic granulates]
F Jung1, C Mrowietz, U T Seyfert
1Abteilung für Klinische Hämostaseologie und Transfusionsmedizin, Universität des Saarlandes, Homburg/Saar.
Abstract:
The adherence of platelets to different polymer granulates was examined in a perfusion chamber filled with platelet-rich plasma. The surface area of each of the granulates was of a standardised size. The results were compared with those found for a non-thrombogenic and a highly thrombogenic foreign-body surface. The three polymers examined-Cryolite, Styrolux and Zylar-must be considered non-thrombogenic. Platelet adherence to these substances is significantly less (3%) than that to a highly thrombogenic surface such as glass (95%). The three materials did not differ in terms of platelet adherence, and would appear to be suitable potential materials for use in cell separators.