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[Blood viscosity analyzer]

N A Dobrovol'skiĭ, Iu M Lopukhin, A S Parfenov

    Meditsinskaia Tekhnika
    |May 1, 1997
    PubMed
    Summary

    A new analyzer measures blood viscosity using a rotating magnetic field and a floating rotor. This device aids in diagnosing diseases linked to microcirculatory and coagulative disorders.

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    Area of Science:

    • Biomedical Engineering
    • Hematology
    • Medical Diagnostics

    Background:

    • Blood viscosity is a critical parameter in assessing microcirculatory and coagulative disorders.
    • Accurate and efficient measurement of blood viscosity is essential for disease diagnosis and management.

    Purpose of the Study:

    • To design and develop a novel analyzer for determining blood viscosity at various shear rates.
    • To validate the analyzer's capability for diagnosing diseases associated with altered blood rheology.

    Main Methods:

    • The analyzer employs rotational viscometry with a freely floating rotor within a thermostabilized measuring cylinder.
    • A rotating magnetic field induces rotor rotation, enabling the measurement of shear stress and calculation of viscosity.
    • Viscosity is calculated based on the stator current squared divided by the rotor's rotational speed.

    Main Results:

    • The analyzer accurately measures blood viscosity in the range of 0.7-14 mPa·sec at shear rates of 20-200 sec⁻¹.
    • The device requires a minimal sample volume of less than 1 cm³.
    • The developed analyzer demonstrates potential for diagnosing conditions involving microcirculatory and coagulative dysfunctions.

    Conclusions:

    • The designed blood viscosity analyzer offers a precise and efficient method for rheological assessment.
    • Its ability to operate with small sample volumes and across a relevant shear rate range makes it suitable for clinical diagnostics.
    • This technology can significantly contribute to the early detection and understanding of diseases influenced by blood rheology.

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