[Presence of a monoclonal component IgG lambda in a 17-day-old newborn with omphalitis caused by Staphylococcus...

Monoclonal components are usually found in elderly patients. They are rarely noted in children, both because of their slight presence, and because the very low concentration makes it difficult to single them out. This report is about the identification of a transitory IgG lambda monoclonal component in a 17 day old baby suffering from aureus Staphylococcus. Electrophoresis was carried out with automatic equipment on cellulose acetate; immunofixation with a manual method on agarose gel; the quantitative doses of the immunoglobulins, reactive protein C and alpha 1-acid glycoprotein with nephelometric technique, the erythrocyte sedimentation rate with automatic equipment. The importance of singling out monoclonal components in children must be emphasized, inasmuch as it may be a sign of an immunological disorder, usually benign and transitory, but sometimes extremely serious.