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The antiphospholipid antibody syndrome: an overview
J L Atterbury1, M B Munn, L J Groome
1Department of Obstetrics and Gynecology, University of South Alabama, Mobile 36617, USA.
Journal of Obstetric, Gynecologic, and Neonatal Nursing : JOGNN
|October 6, 1997
Summary
Antiphospholipid antibody syndrome (APS) involves maternal antibodies causing pregnancy loss and clotting. Pregnant patients with APS face risks, necessitating careful management and monitoring for adverse outcomes.
Area of Science:
- Obstetrics and Gynecology
- Immunology
- Hematology
Background:
- Antiphospholipid antibody syndrome (APS) is an autoimmune disorder.
- Characterized by anticardiolipin antibodies and/or lupus anticoagulant.
- Associated with recurrent pregnancy loss, thrombotic events, and thrombocytopenia.
Purpose of the Study:
- To review antiphospholipid antibody syndrome (APS).
- To discuss pathophysiology, clinical sequelae, diagnostic criteria, and management.
- To highlight risks for adverse maternal and perinatal outcomes in pregnant patients.
Main Methods:
- Literature review of antiphospholipid antibody syndrome (APS).
- Synthesis of information on pathophysiology and clinical manifestations.
- Compilation of diagnostic criteria and treatment strategies.
Main Results:
- APS is rare but carries significant risks for pregnant patients.
- Adverse maternal and perinatal outcomes are associated with APS.
- Comprehensive management is crucial for patients with APS.
Conclusions:
- Antiphospholipid antibody syndrome (APS) requires thorough understanding for effective patient care.
- Early diagnosis and management can mitigate risks.
- Multidisciplinary approach including nursing care is vital.