Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Candidal mediastinitis: an emerging clinical entity

C J Clancy1, M H Nguyen, A J Morris

  • 1University of Florida College of Medicine and the Veterans Administration Medical Center, Gainesville 32610, USA.

Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
|October 6, 1997
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Corrigendum to "Safety and clinical activity of BMS-986365 (CC-94676), a dual androgen receptor ligand-directed degrader and antagonist, in heavily pretreated patients with metastatic castration-resistant prostate cancer": [Ann Oncol 36 (2025) 76-88].

Annals of oncology : official journal of the European Society for Medical Oncology·2026
Same author

Hydropower reservoirs - their potential association with transmission of trematodes in Vietnam.

Journal of helminthology·2025
Same author

Safety and clinical activity of BMS-986365 (CC-94676), a dual androgen receptor ligand-directed degrader and antagonist, in heavily pretreated patients with metastatic castration-resistant prostate cancer.

Annals of oncology : official journal of the European Society for Medical Oncology·2024
Same author

Prevalence of healthcare-associated infections in public hospitals in New Zealand, 2021.

The Journal of hospital infection·2022
Same author

Mental Disorders and Oral Diseases: Future Research Directions.

Journal of dental research·2022
Same author

Multicenter Registry of Patients Receiving Systemic Mold-Active Triazoles for the Management of Invasive Fungal Infections.

Infectious diseases and therapy·2022

Candidal mediastinitis, a rare fungal infection post-thoracic surgery, presents with varied symptoms. Early diagnosis and aggressive treatment combining surgery and antifungals are crucial for improving patient outcomes.

Area of Science:

  • Medical Mycology
  • Thoracic Surgery

Background:

  • Candidal mediastinitis is a rare but serious complication following thoracic surgery.
  • Diagnosis is often delayed due to challenges in specimen collection and interpretation of Candida cultures.

Observation:

  • Nine cases of candidal mediastinitis were identified, all occurring post-thoracic surgery.
  • Common symptoms included chest wall erythema, drainage, fever, and sternal instability.
  • A significant delay in diagnosis was noted in one-third of cases.

Findings:

  • The mortality rate for candidal mediastinitis was 56%.
  • Complications such as contiguous or hematogenous spread occurred in 78% of patients.
  • Delayed diagnosis and treatment contributed to poor outcomes.

Related Experiment Videos

Implications:

  • Aggressive surgical debridement combined with a minimum of 6 weeks of antifungal therapy is recommended.
  • Prompt recognition and initiation of appropriate treatment are critical for improving prognosis.
  • Further research is needed to define optimal therapeutic strategies for this rare condition.