Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Selenium and cardiovascular diseases--an update

J K Huttunen1

  • 1National Public Health Institute, Helsinki, Finland.

Biomedical and Environmental Sciences : BES
|October 7, 1997
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Is dietary salt restriction highly dangerous?].

Duodecim; laaketieteellinen aikakauskirja·2001
Same author

Alpha-tocopherol (vitamin E) and beta-carotene supplementation does not affect the risk for large abdominal aortic aneurysm in a controlled trial.

Atherosclerosis·2001
Same author

Effects of supplemental alpha-tocopherol and beta-carotene on urinary tract cancer: incidence and mortality in a controlled trial (Finland).

Cancer causes & control : CCC·2001
Same author

Life-style factors and risk for abdominal aortic aneurysm in a cohort of Finnish male smokers.

Epidemiology (Cambridge, Mass.)·2001
Same author

Implications of serum pepsinogen I in early endoscopic diagnosis of gastric cancer and dysplasia. Helsinki Gastritis Study Group.

Scandinavian journal of gastroenterology·2000
Same author

Prospective study of diet, lifestyle, and intermittent claudication in male smokers.

American journal of epidemiology·2000

Low selenium intake may contribute to heart disease, including cardiomyopathy and atherosclerosis. More research, specifically controlled trials, is needed to confirm selenium

Area of Science:

  • Nutritional science
  • Cardiovascular medicine
  • Epidemiology

Background:

  • Dietary selenium deficiency is implicated in cardiovascular disease (CVD) etiology.
  • Cardiomyopathy linked to low selenium intake observed in specific populations and TPN patients.
  • Epidemiological data suggests a potential role for selenium deficiency in atherosclerotic disease.

Purpose of the Study:

  • To review the evidence linking selenium intake to cardiovascular diseases.
  • To assess the association between selenium levels and ischemic heart disease and atherosclerosis.
  • To identify the need for further research, particularly controlled trials.

Main Methods:

  • Review of epidemiological studies examining selenium intake and cardiovascular disease incidence.

Related Experiment Videos

  • Analysis of population comparisons showing an inverse association between ischemic heart disease and selenium intake.
  • Evaluation of conflicting results from longitudinal studies on serum selenium levels and coronary disease risk.

    • Main Results:

    • Low selenium intake is associated with cardiomyopathy in specific geographic areas and in patients on total parenteral nutrition.
    • Population studies suggest an inverse relationship between selenium intake and ischemic heart disease incidence.
    • Longitudinal studies yield conflicting results regarding serum selenium levels and coronary heart disease risk.

    Conclusions:

    • Selenium deficiency is a potential etiological factor in cardiovascular diseases, including atherosclerosis.
    • Conflicting evidence from longitudinal studies necessitates further investigation.
    • Controlled prevention trials are essential to establish the definitive role of selenium in preventing atherosclerotic disease.