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Anorexia of aging: physiologic and pathologic

J E Morley1

  • 1Division of Geriatrics, St Louis University Medical School, MO 63104, USA. Morley@SLU.EDU

The American Journal of Clinical Nutrition
|October 10, 1997
PubMed
Summary
This summary is machine-generated.

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Older adults experience reduced food intake due to physiological anorexia, increasing malnutrition risk. Understanding aging

Area of Science:

  • Gerontology
  • Nutritional Science
  • Metabolic Regulation

Background:

  • Aging is paradoxically associated with increased body fat but decreased food intake.
  • This leads to a physiological anorexia of aging, impacting nutritional status.
  • Older adults are at high risk for protein-energy malnutrition, often unrecognized and undertreated.

Purpose of the Study:

  • To explain the mechanisms behind the physiological anorexia of aging.
  • To identify factors contributing to reduced food intake in the elderly.
  • To highlight the risks and management of malnutrition in older populations.

Main Methods:

  • Review of existing animal and human studies on aging and food intake.
  • Analysis of hormonal and neurotransmitter changes associated with aging.

Related Experiment Videos

  • Examination of the link between anorexia, malnutrition, and disease in older adults.

    • Main Results:

    • Aging involves decreased physical activity and altered metabolism, contributing to anorexia.
    • Hormonal changes, such as increased cholecystokinin and potentially decreased opioid drive, play a role.
    • Physiological anorexia increases the risk of protein-energy malnutrition in older individuals.

    Conclusions:

    • Physiological anorexia of aging is a complex condition influenced by metabolic and hormonal shifts.
    • Early detection and appropriate management of malnutrition are crucial for older adults.
    • Further research is needed for effective appetite-enhancing treatments in the elderly.